9LSS

The crystal structure of PDE5 with 1934

This is a non-PDB format compatible entry.

Summary for 9LSS

• Entry DOI: 10.2210/pdb9lss/pdb
• Descriptor: cGMP-specific 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: pde5 inhibitor, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 100741.10

Authors

Wu, D.,Huang, Y.-Y.,Luo, H.-B. (deposition date: 2025-02-04, release date: 2026-02-18)

• Primary citation: Wu, D.,Huang, Y.-Y.,Luo, H.-B.; Organocatalytic Enantioselective Synthesis and Optimization of Evodiamine Derivatives as Potent and Highly Selective PDE5 Allosteric Inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.50007004666 Å)