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9LQI

Structure of Nanobody-161 in complex of Tumor necrosis factor receptor 2 (TNFR2)

Summary for 9LQI
Entry DOI10.2210/pdb9lqi/pdb
DescriptorNanobody-161 (B chain), Tumor necrosis factor receptor superfamily member 1B (2 entities in total)
Functional Keywordstnfr2, non-blocking, nanobody-161, cancer, tregs, adcc, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight76283.58
Authors
Fan, S.,Lang, G.,Zhou, J. (deposition date: 2025-01-28, release date: 2026-08-05)
Primary citationFan, S.,Lang, G.,Zhou, J.
Structure of Nanobody-161 in complex of Tumor necrosis factor receptor 2 (TNFR2) reveals a non-blocking mechanism for cancer therap
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.95 Å)
Structure validation

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