9LQA

Crystal structure of NrN E21A in complex with SAM-AMP

This is a non-PDB format compatible entry.

Summary for 9LQA

• Entry DOI: 10.2210/pdb9lqa/pdb
• Descriptor: NrN, [(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-4-oxidanyl-oxolan-2-yl]methyl-[(3~{S})-3-azanyl-4-oxidanyl-4-oxidanylidene-butyl]-methyl-sulfanium, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• Functional Keywords: enzyme, phosphodiesterase, crispr-cas system, second messenger, immune system
• Biological source: Bacteroides fragilis
• Total number of polymer chains: 1
• Total formula weight: 30847.81

Authors

Duan, B.,Zhao, B. (deposition date: 2025-01-28, release date: 2025-11-26)

• Primary citation: Duan, B.,Zhao, B.; Mechanisms of SAM-AMP synthesis and degradation in antiviral type III CRISPR signaling.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.91 Å)