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9LPK

Structure of human PADI6-UHRF1-UBE2D3 complex

Summary for 9LPK
Entry DOI10.2210/pdb9lpk/pdb
EMDB information63270
DescriptorE3 ubiquitin-protein ligase UHRF1, Protein-arginine deiminase type-6, Ubiquitin-conjugating enzyme E2 D3 (3 entities in total)
Functional Keywordspadi6, uhrf1, ube2d3, ubiquitylation, maternal complex, early embryonic development, ligase/hydrolase, ligase-hydrolase complex
Biological sourceHomo sapiens (human)
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Total number of polymer chains6
Total formula weight368920.70
Authors
Li, J.,Deng, D. (deposition date: 2025-01-25, release date: 2026-01-28)
Primary citationLi, J.,Deng, D.
An essential maternal PADI6-UHRF1-UBE2D (MPU) complex regulates protein ubiquitination during oocyte maturation and embryogenesis
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.03 Å)
Structure validation

248942

PDB entries from 2026-02-11

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