9LPD

Crystal structure of Escherichia coli trptophanyl-tRNA synthetase in complex with tirabrutinib

This is a non-PDB format compatible entry.

Summary for 9LPD

• Entry DOI: 10.2210/pdb9lpd/pdb
• Descriptor: Tryptophan--tRNA ligase, Tirabrutinib, SULFATE ION, ... (6 entities in total)
• Functional Keywords: trptophayl-trna synthetase, tirabrutinib, complex, ligase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 78193.14

Authors

Peng, X.,Chen, B.,Xia, K.,Zhou, H. (deposition date: 2025-01-24, release date: 2025-05-07)

• Primary citation: Peng, X.,Xia, K.,Huang, Q.,Xiang, M.,Han, L.,Qiu, H.,Gu, Q.,Chen, B.,Zhou, H.; The lineage-specific tRNA recognition mechanism of bacterial trptophanyl-tRNA synthetase and its implications for inhibitor discover; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.05 Å)