9LOF

Cryo-EM structure of SFTSV Gn in complex with ZS01S-336

Summary for 9LOF

Entry DOI	10.2210/pdb9lof/pdb
EMDB information	63247
Descriptor	Envelopment polyprotein, heavy chain of 336, light chain of 336, ... (5 entities in total)
Functional Keywords	viral glycoprotein, neutralizing antibody, viral protein
Biological source	Severe fever with thrombocytopenia syndrome virus More
Total number of polymer chains	3
Total formula weight	84307.31
Authors	Bi, J.H.,Zhang, Y.Y.,Zhou, Q.,Li, D.P. (deposition date: 2025-01-23, release date: 2026-01-28, Last modification date: 2026-02-18)
Primary citation	Bi, J.H.,Dai, Z.,Hong, X.,Zhang, Y.,Lu, S.,Wang, Q.,Liu, Y.,Li, X.,Li, M.,Song, G.,Chen, Q.,Yu, W.,Yang, Y.,Ma, Y.,Liu, H.,Meng, X.,Wang, Z.,Liu, D.,Sun, R.,Sun, Q.,Li, S.,Zhou, Q.,Li, D. Single-Dose Therapeutic Antibody Protects against SFTSV in Mice and Rhesus Macaques Vita, 2026 Cited by DOI: 10.15302/vita.2025.12.0002 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.03 Å)

Structure validation