9LOE

Cryo-EM structure of SFTSV Gn in complex with ZS004-1C5

Summary for 9LOE

Entry DOI	10.2210/pdb9loe/pdb
EMDB information	63246
Descriptor	Envelopment polyprotein, heavy chain of YSJ1C5, light chain of YSJ1C5, ... (5 entities in total)
Functional Keywords	viral glycoprotein, neutralizing antibody, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Severe fever with thrombocytopenia syndrome virus More
Total number of polymer chains	3
Total formula weight	84071.99
Authors	Bi, J.H.,Zhang, Y.Y.,Zhou, Q.,Li, D.P. (deposition date: 2025-01-23, release date: 2026-01-28, Last modification date: 2026-02-18)
Primary citation	Bi, J.H.,Dai, Z.,Hong, X.,Zhang, Y.,Lu, S.,Wang, Q.,Liu, Y.,Li, X.,Li, M.,Song, G.,Chen, Q.,Yu, W.,Yang, Y.,Ma, Y.,Liu, H.,Meng, X.,Wang, Z.,Liu, D.,Sun, R.,Sun, Q.,Li, S.,Zhou, Q.,Li, D. Single-Dose Therapeutic Antibody Protects against SFTSV in Mice and Rhesus Macaques Vita, 2026 Cited by DOI: 10.15302/vita.2025.12.0002 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.99 Å)

Structure validation