9LLE

Cryo-EM structure of D1R-Gs in complex with de novo designed GEM targeting TM1/2/4

Summary for 9LLE

• Entry DOI: 10.2210/pdb9lle/pdb
• EMDB information: 63199
• Descriptor: D(1A) dopamine receptor,Expression tag, De novo designed GPCR exoframe modulator targeting TM1/2/4, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total)
• Functional Keywords: gpcr, gem, gpcr exoframe modulator, d1r, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 200239.76

Authors

Guo, J.,Zhou, Y.,Cheng, S.,Zhang, Y. (deposition date: 2025-01-17, release date: 2026-03-04)

• Primary citation: Cheng, S.,Guo, J.,Zhou, Y.,Zhang, Y.; GPCR exoframe modulator; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.9 Å)