9LA8

Comparative analysis of functions and catalytic mechanisms of methyltransferases involved in anthracycline biosynthesis

This is a non-PDB format compatible entry.

Summary for 9LA8

• Entry DOI: 10.2210/pdb9la8/pdb
• Descriptor: Methyltransferase domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE, (7~{S},9~{S})-7-[(2~{R},4~{S},5~{S},6~{S})-4-azanyl-6-methyl-5-oxidanyl-oxan-2-yl]oxy-9-ethyl-4-methoxy-6,9,11-tris(oxidanyl)-8,10-dihydro-7~{H}-tetracene-5,12-dione, ... (4 entities in total)
• Functional Keywords: dnrk, transferase
• Biological source: Streptomyces coeruleorubidus
• Total number of polymer chains: 2
• Total formula weight: 83858.60

Authors

Yang, Q.Y.,Sang, M.L.,Zhang, W. (deposition date: 2025-01-01, release date: 2026-01-07)

• Primary citation: Yang, Q.Y.,Sang, M.L.,Zhang, W.; Comparative analysis of functions and catalytic mechanisms of methyltransferases involved in anthracycline biosynthesis; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.56 Å)