9L6M

Crystal Structure of BRD2 BD1 domain in complex with small molecule inhibitor Isoxazole azepine compound.

Summary for 9L6M

• Entry DOI: 10.2210/pdb9l6m/pdb
• Descriptor: Bromodomain-containing protein 2, 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-[1,2]oxazolo[5,4-c]thieno[2,3-e]azepin-6-yl]acetamide (3 entities in total)
• Functional Keywords: bromodomain, inhibitor, small molecule, drug discovery, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 55319.46

Authors

Jwala, N.,Vijayshankar, N.,Thomas, A.,NarasimhaRao, K. (deposition date: 2024-12-24, release date: 2025-12-24)

• Primary citation: Jwala, N.,NarasimhaRao, K.; Crystal Structure of BRD2 BD1 domain in complex with small molecule inhibitor CPI-0610 Pelabresib.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.78 Å)