9L69

Structure of the human cGAS with 2'3'-cGUMP

This is a non-PDB format compatible entry.

Summary for 9L69

• Entry DOI: 10.2210/pdb9l69/pdb
• Descriptor: Cyclic GMP-AMP synthase, ZINC ION, 2'3'-cGMP-UMP, ... (4 entities in total)
• Functional Keywords: cgas, cgump, cgamp, dna binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 119260.60

Authors

Zhou, R.,Zhan, X. (deposition date: 2024-12-24, release date: 2026-07-01)

• Primary citation: Zhou, R.,Zhan, X.,Zhang, Z.,Shi, Y.; Human cGAS synthesizes cyclic GMP-UMP to activate the STING signaling pathway; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.09 Å)