9L62

A novel allosteric covalent inhibitory site of fucosyltransferase 8 revealed by crystal structures

Summary for 9L62

• Entry DOI: 10.2210/pdb9l62/pdb
• Descriptor: Alpha-(1,6)-fucosyltransferase, 1-[6-[azanylidene-[[azanylidene-[[(4-chlorophenyl)amino]methyl]-$l^{4}-azanyl]methyl]-$l^{4}-azanyl]hexyl]-3-[~{N}-(4-chlorophenyl)carbamimidoyl]guanidine (3 entities in total)
• Functional Keywords: inhibitor, complex, allosteric, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 115783.04

Authors

Fang, P.,Jiang, J. (deposition date: 2024-12-23, release date: 2026-01-07)

• Primary citation: Fang, P.,Jiang, J.; A novel allosteric covalent inhibitory site of fucosyltransferase 8 revealed by crystal structures; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.04 Å)