9L46

ATR-ATRIP-bound with AMP-PNP

Summary for 9L46

• Entry DOI: 10.2210/pdb9l46/pdb
• EMDB information: 62807
• Descriptor: Serine/threonine-protein kinase ATR, ATR-interacting protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (3 entities in total)
• Functional Keywords: atr-atrip inhibitor, cell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 776441.38

Authors

Wang, G. (deposition date: 2024-12-20, release date: 2025-05-21)

• Primary citation: Wang, G.,Wang, P.,Zheng, Z.,Zhang, Q.,Xu, C.,Xu, X.,Jian, L.,Zhao, Z.,Cai, G.,Wang, X.; Molecular architecture and inhibition mechanism of human ATR-ATRIP; Sci Bull (Beijing), 2025; DOI: 10.1016/j.scib.2025.05.009

Experimental method

ELECTRON MICROSCOPY (6.29 Å)