9KXZ

Structure of human B0AT1-ACE2 complex with compound1

This is a non-PDB format compatible entry.

Summary for 9KXZ

• Entry DOI: 10.2210/pdb9kxz/pdb
• Related: 9KXU
• EMDB information: 62633
• Descriptor: Sodium-dependent neutral amino acid transporter B(0)AT1, Angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: inhibitor, amino acid transporter, slc6, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 337293.49

Authors

Imazu, T.,Miyaguchi, I.,Hiraizumi, M. (deposition date: 2024-12-07, release date: 2025-12-10)

• Primary citation: Imazu, T.,Akashi, T.,Hiraizumi, M.,Inui, Y.,Sasaki, W.,Takahashi, T.,Todoroki, H.,Kumanomidou, T.,Hisano, H.,Asada, H.,Kusakizako, T.,Nishizawa, T.,Iwata, S.,Nureki, O.,Miyaguchi, I.; Structure-guided development of a potent human B0AT1 inhibitor that shows activity in a model mouse of Phenylketonuria; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.8 Å)