9KXU

Structure of human B0AT1-ACE2 complex with compound 2

This is a non-PDB format compatible entry.

Summary for 9KXU

• Entry DOI: 10.2210/pdb9kxu/pdb
• EMDB information: 62628
• Descriptor: Sodium-dependent neutral amino acid transporter B(0)AT1, Angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: inhibitor, amino acid transporter, slc6, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 166949.14

Authors

Hiraizumi, M.,Miyaguchi, I. (deposition date: 2024-12-07, release date: 2025-12-10)

• Primary citation: Imazu, T.,Akashi, T.,Hiraizumi, M.,Inui, Y.,Sasaki, W.,Takahashi, T.,Todoroki, H.,Kumanomidou, T.,Hisano, H.,Asada, H.,Kusakizako, T.,Nishizawa, T.,Iwata, S.,Nureki, O.,Miyaguchi, I.; Structure-guided development of a potent human B0AT1 inhibitor effective in a mouse model of phenylketonuria; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.87 Å)