9K8R

Structure of Promiscuous short chain dehydrogenase Spm14 in complex with NADPH

Summary for 9K8R

• Entry DOI: 10.2210/pdb9k8r/pdb
• Descriptor: Spm14, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
• Functional Keywords: short chain dehydrogenase, coenzyme, nadph, biosynthetic protein
• Biological source: Spiromastix sp. SCSIO F190
• Total number of polymer chains: 2
• Total formula weight: 63485.73

Authors

Jing, L.Q.,Peng, M.,Chen, Y.Y.,Ju, J.H.,Wu, D.L. (deposition date: 2024-10-24, release date: 2025-02-12)

• Primary citation: Jing, L.Q.,Chen, Y.Y.,Peng, M.,Ju, J.H.,Wu, D.L.; Biosynthesis of Spiromarmycin Reveals the Unusual Formation of Benzopyran and the Mechanistic Insight of a Promiscuous Short Chain reductase Spm14; to be published,

Experimental method

X-RAY DIFFRACTION (3.1 Å)