9K4P

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state EA2.3

Summary for 9K4P

Entry DOI	10.2210/pdb9k4p/pdb
EMDB information	62066
Descriptor	26S proteasome regulatory subunit 7, Proteasome subunit alpha type-7, Proteasome subunit alpha type-5, ... (38 entities in total)
Functional Keywords	proteasome, aaa-atpase, deubiquitinase, hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	49
Total formula weight	1684973.80
Authors	Wu, Z.,Chen, E.,Mao, Y. (deposition date: 2024-10-21, release date: 2026-04-29)
Primary citation	Wu, Z.,Chen, E.,Zou, S.,Hou, Y.,Zhang, S.,Wang, W.,Dong, Y.,Mao, Y. Hidden dynamics of ubiquitin-mediated proteasome autoregulation during protein degradation To be published,
Experimental method	ELECTRON MICROSCOPY (4.8 Å)

Structure validation