9K36

Human RNA Polymerase III de novo transcribing complex 12 (TC12)

Summary for 9K36

• Entry DOI: 10.2210/pdb9k36/pdb
• EMDB information: 62006
• Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerases I and III subunit RPAC2, ... (25 entities in total)
• Functional Keywords: elongation complex, transcription/dna/rna, transcription-dna-rna complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 21
• Total formula weight: 792556.80

Authors

Wang, Q.,Ren, Y.,Jin, Q.,Chen, X.,Xu, Y. (deposition date: 2024-10-18, release date: 2025-04-16, Last modification date: 2025-06-11)

• Primary citation: Wang, Q.,Ren, Y.,Jin, Q.,Chen, X.,Xu, Y.; Structural insights into human Pol III transcription initiation in action; Nature, 2025; DOI: 10.1038/s41586-025-09093-w

Experimental method

ELECTRON MICROSCOPY (2.9 Å)