9K2E

Crystal structure of mSMPDL3B-dimer

9K2E の概要

• エントリーDOI: 10.2210/pdb9k2e/pdb
• 分子名称: Acid sphingomyelinase-like phosphodiesterase 3b, 2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (5 entities in total)
• 機能のキーワード: dimer, n-glycosylation, gpi-anchor, lipid-modulating phosphodiesterase., hydrolase
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 97458.82

構造登録者

Zhang, C.G.,Hou, Y.F.,Liu, P.Y.,Fan, S.L. (登録日: 2024-10-17, 公開日: 2025-10-22)

• 主引用文献: Zhang, C.G.,Hou, Y.F.; Membrane integrity changes upon viral infection activate sphingomyelinase SMPDL3B to restrict cGAS-STING signaling via cGAMP degradation; To Be Published,

実験手法

X-RAY DIFFRACTION (2.02 Å)