9JO1

NMR Solution structure of the 2:1 Berberine-BLM-G4 Complex

Summary for 9JO1

• Entry DOI: 10.2210/pdb9jo1/pdb
• Descriptor: DNA (5'-D(*TP*GP*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*GP*GP*AP*GP*GP*GP*AP*AP*T*)-3'), BERBERINE (2 entities in total)
• Functional Keywords: blm promoter, g-quadruplex, nmr solution structure, dna, berberine
• Biological source: Homo sapiens
• Total number of polymer chains: 1
• Total formula weight: 7371.04

Authors

Wang, K.B. (deposition date: 2024-09-24, release date: 2026-04-01)

• Primary citation: Wang, Y.Y.,Bian, Y.T.,Chen, X.Y.,Li, J.Z.,Liu, Y.S.,Kong, L.Y.,Wang, K.B.; BLM G-quadruplex stabilizers synergize with PARP inhibitor to kill BRCA wild-type colon cancer cells; To Be Published,

Experimental method

SOLUTION NMR