9JNE

Crystal Structure of SME-1 E166A mutant in complex with Doripenem

Summary for 9JNE

• Entry DOI: 10.2210/pdb9jne/pdb
• Descriptor: beta-lactamase, (2S,3R,4S)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• Functional Keywords: acyl enzyme complex, carbapenemase, dbo, hydrolase
• Biological source: Serratia marcescens
• Total number of polymer chains: 2
• Total formula weight: 61942.04

Authors

Dhankhar, K.,Hazra, S. (deposition date: 2024-09-23, release date: 2025-10-01)

• Primary citation: Dhankhar, K.,Hazra, S.; Crystal Structure of SME-1 E166A mutant in complex with Doripenem; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)