9JJS

Crystal Structure of human Pin1 catalytic domain in complex with a covalent inhibitor

This is a non-PDB format compatible entry.

Summary for 9JJS

• Entry DOI: 10.2210/pdb9jjs/pdb
• Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, methyl (~{E})-4-[[(3~{R})-1,1-bis(oxidanylidene)thiolan-3-yl]amino]-4-oxidanylidene-but-2-enoate (3 entities in total)
• Functional Keywords: human pin1 catalytic domain; peptidyl-prolyl cis-trans isomerase nima-interacting 1; covalent inhibitor, isomerase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 27300.32

Authors

Wang, X.Y.,Tian, M.Z.,Zhou, J.,Xu, B.L. (deposition date: 2024-09-14, release date: 2026-03-25)

• Primary citation: Wang, X.Y.,Tian, M.Z.,Zhou, J.,Xu, B.L.; Crystal Structure of human Pin1 catalytic domain in complex with a covalent inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.52 Å)