9JHL

Cryo-EM structure of CpAgo_gDNA-tg_dsDNA dimeric ternary complex

Summary for 9JHL

• Entry DOI: 10.2210/pdb9jhl/pdb
• EMDB information: 61486
• Descriptor: Clostridium perfringen Argonaute, DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), DNA (29-MER), ... (4 entities in total)
• Functional Keywords: pagos, dimerization, nucleotide-binding pocket, paz, cryo-em, dna binding protein/dna, dna binding protein-dna complex
• Biological source: Clostridium perfringenosum; More
• Total number of polymer chains: 6
• Total formula weight: 203496.19

Authors

Liu, Y.,Li, S.,Zhang, K. (deposition date: 2024-09-10, release date: 2025-07-30)

• Primary citation: Liu, Y.,Li, S.,Zhang, K.; Dimeric state and novel nucleotide-binding pocket drive CpAgo-mediated DNA cleavage; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.86 Å)