9JH8

Cryo-EM structure of CpAgo_gDNA-tg_ssDNA monomeric ternary complex

Summary for 9JH8

• Entry DOI: 10.2210/pdb9jh8/pdb
• EMDB information: 61475
• Descriptor: Clostridium perfringens Argonaute (CpAgo), DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), DNA (5'-D(*AP*CP*T*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'), ... (4 entities in total)
• Functional Keywords: pagos, nucleotide-binding pocket, paz, cryo-em, dna binding protein/dna, dna binding protein-dna complex
• Biological source: Clostridium perfringens; More
• Total number of polymer chains: 3
• Total formula weight: 99239.56

Authors

Liu, Y.,Li, S.,Zhang, K. (deposition date: 2024-09-09, release date: 2025-07-30)

• Primary citation: Liu, Y.,Li, S.,Zhang, K.; Dimeric state and novel nucleotide-binding pocket drive CpAgo-mediated DNA cleavage; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.81 Å)