9JGX

Crystal structure of SARS-Cov-2 main protease E166N mutant in complex with Ibuzatrelvir

Summary for 9JGX

• Entry DOI: 10.2210/pdb9jgx/pdb
• Descriptor: 3C-like proteinase nsp5, N-(methoxycarbonyl)-3-methyl-L-valyl-(4R)-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-(trifluoromethyl)-L-prolinamide (3 entities in total)
• Functional Keywords: viral protein-inhibitor complex, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• Total number of polymer chains: 1
• Total formula weight: 33882.61

Authors

Zhao, Z.Y.,Jiang, H.H.,Zhang, J.,Li, J. (deposition date: 2024-09-08, release date: 2026-03-11)

• Primary citation: Zhao, Z.Y.,Jiang, H.H.,Zhang, J.,Li, J.; Crystal structure of SARS-Cov-2 main protease E166N mutant in complex with Ibuzatrelvir; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.07 Å)