9JGU

Crystal structure of HCoV-NL63 main protease with Ibuzatrelvir

Summary for 9JGU

• Entry DOI: 10.2210/pdb9jgu/pdb
• Descriptor: 3C-like proteinase, N-(methoxycarbonyl)-3-methyl-L-valyl-(4R)-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-(trifluoromethyl)-L-prolinamide (3 entities in total)
• Functional Keywords: viral protein-inhibitor complex, viral protein
• Biological source: Human coronavirus NL63
• Total number of polymer chains: 2
• Total formula weight: 65510.23

Authors

Zhou, X.L.,Zeng, X.Y.,Zhang, J.,Li, J. (deposition date: 2024-09-08, release date: 2026-03-11)

• Primary citation: Zhou, X.L.,Zeng, X.Y.,Zhang, J.,Li, J.; Crystal structure of HCoV-NL63 main protease with Ibuzatrelvir; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.92 Å)