9JF6

Crystal Structure of human Pin1 in complex with a covalent inhibitor

This is a non-PDB format compatible entry.

Summary for 9JF6

• Entry DOI: 10.2210/pdb9jf6/pdb
• Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, methyl (~{Z})-4-[1-benzothiophen-2-ylmethyl-[(3~{S})-1,1-bis(oxidanylidene)thiolan-3-yl]amino]-4-oxidanylidene-but-2-enoate, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL (3 entities in total)
• Functional Keywords: human pin1; complex structure; covalent inhibitor; peptidyl-prolyl cis-trans isomerase nima-interacting 1, isomerase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 18339.40

Authors

Wang, X.Y.,Tian, M.Z.,Zhou, J.,Xu, B.L. (deposition date: 2024-09-04, release date: 2026-03-11)

• Primary citation: Wang, X.Y.,Tian, M.Z.,Zhou, J.,Xu, B.L.; Crystal Structure of human Pin1 in complex with a covalent inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.96 Å)