9JBE

Cryo-EM structure of the human LYCHOS in complex with cholesterol and cholesteryl hemisuccinate in the contracted state

This is a non-PDB format compatible entry.

Summary for 9JBE

• Entry DOI: 10.2210/pdb9jbe/pdb
• EMDB information: 61311
• Descriptor: Lysosomal cholesterol signaling protein, CHOLESTEROL HEMISUCCINATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... (6 entities in total)
• Functional Keywords: permease-like domain, gpcr-like domain, cholesterol, mtorc1, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 206019.97

Authors

Yu, S.,Liang, L. (deposition date: 2024-08-27, release date: 2025-07-16)

• Primary citation: Yu, S.,Liang, L.; Structural insights into cholesterol sensing by the LYCHOS-mTORC1 pathway; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.31 Å)