9J04

Cryo-EM structure of hOAT1 in complex with cidofovir

Summary for 9J04

Entry DOI	10.2210/pdb9j04/pdb
EMDB information	61048
Descriptor	Solute carrier family 22 member 6, ({[(2S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid (2 entities in total)
Functional Keywords	transporter, organic anion, uptake, renal pathophysiology, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	62148.21
Authors	Yang, D.X.,Luo, Y.B.,Wu, X.N. (deposition date: 2024-08-02, release date: 2025-08-13)
Primary citation	Wu, X.N.,Luo, Y.B.,Feng, S.J. Structural basis for recognition of two different drugs by human OAT1 To be published,
Experimental method	ELECTRON MICROSCOPY (3.15 Å)

Structure validation