9IZV

Cryo-EM structure of ALDH6A1-Y172H & R535C

Summary for 9IZV

• Entry DOI: 10.2210/pdb9izv/pdb
• EMDB information: 61043
• Descriptor: Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial (1 entity in total)
• Functional Keywords: aldh6a1, y172h, r535c, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 221393.86

Authors

Su, G.,Xu, Y.,Luan, X. (deposition date: 2024-08-01, release date: 2024-11-27)

• Primary citation: Su, G.,Ju, K.,Xu, Y.,Jin, Y.,Chen, L.,Luan, X.; Structural and biochemical basis for the pathogenic mutations of methylmalonate semialdehyde dehydrogenase ALDH6A1; Medicine Plus, 1:100056-, 2024; DOI: 10.1016/j.medp.2024.100056

Experimental method

ELECTRON MICROSCOPY (3.02 Å)