9IST

Crystal Structure of Cytochrome P450BM3 VI-18A12 Mutant Heme Domain with N-Decanoyl-L-Homoserine Lactone

Summary for 9IST

Entry DOI	10.2210/pdb9ist/pdb
Descriptor	Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, N-[(3S)-2-oxotetrahydrofuran-3-yl]decanamide, ... (6 entities in total)
Functional Keywords	p450, monooxygenase, decoy molecules, oxidoreductase
Biological source	Priestia megaterium
Total number of polymer chains	2
Total formula weight	106993.71
Authors	Yokoyama, Y.,Sugimoto, H.,Shoji, O. (deposition date: 2024-07-18, release date: 2024-12-04)
Primary citation	Yokoyama, Y.,Ariyasu, S.,Karasawa, M.,Kasai, C.,Aiba, Y.,Sugimoto, H.,Shoji, O. Bacterial Acyl Homoserine Lactones Triggered Non-Native Substrate Hydroxylation Catalyzed by Directed-Evolution-Derived Cytochrome P450BM3 Mutants Chemcatchem, 2024 Cited by DOI: 10.1002/cctc.202401641 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.27 Å)

Structure validation