9INZ

Hemichannel sub-structure of Cx43/GJA1 gap junction intercellular channel, treated with a 5-molar excess of carbenoxolone

Summary for 9INZ

• Entry DOI: 10.2210/pdb9inz/pdb
• EMDB information: 60713 60717
• Descriptor: Gap junction alpha-1 protein, TETRADECANE (2 entities in total)
• Functional Keywords: gap junction, cx43, inhibitor, carbenoxolone, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 189995.71

Authors

Lee, C.W. (deposition date: 2024-07-08, release date: 2026-01-21)

• Primary citation: Lee, C.W.,Jang, H.S.,Woo, J.S.; Structural insights into the closing mechanism of gap junction intercellular channels by carbenoxolone; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.34 Å)