9ILN

ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to a pyrimidine 2,4-diketone derivative inhibitor

This is a non-PDB format compatible entry.

Summary for 9ILN

• Entry DOI: 10.2210/pdb9iln/pdb
• Descriptor: Poly [ADP-ribose] polymerase 1, processed C-terminus, 5-ethyl-1-[[3-[(3~{R})-4-ethyl-3-(2-hydroxyethyl)piperazin-1-yl]carbonyl-4-fluoranyl-phenyl]methyl]pyrimidine-2,4-dione, SULFATE ION, ... (4 entities in total)
• Functional Keywords: adp-ribosyltransferase 1, parp1, inhibitor, pyrimidine 2, 4-diketone derivative, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 80263.70

Authors

Wang, X.Y.,Tian, S.Y.,Zhou, J.,Xu, B.L. (deposition date: 2024-07-01, release date: 2025-07-09)

• Primary citation: Wang, X.Y.,Tian, S.Y.,Zhou, J.,Xu, B.L.; ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to a inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.49 Å)