9IJR

Cryo-EM structure of the orphan GPR52 beta-arrestin 1 complex bound to ligand c17

Summary for 9IJR

• Entry DOI: 10.2210/pdb9ijr/pdb
• EMDB information: 60642
• Descriptor: G-protein coupled receptor 52, Beta-arrestin-1, scFv30 antibody, ... (4 entities in total)
• Functional Keywords: complex, membrane protein, gpcr, arrestin, beta-arrestin1, membrane protein/immune system, membrane protein-immune system complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 115166.05

Authors

Lin, X.,Xu, F. (deposition date: 2024-06-25, release date: 2025-09-03, Last modification date: 2025-11-19)

• Primary citation: Lin, X.,Wei, X.,Pu, N.,Wang, L.,Zhang, Z.,Li, C.,Yue, Y.,Liu, J.,Tan, Q.,Sun, Q.,Xu, F.; Constitutive arrestin recruitment by orphan GPR52 via an atypical binding mode.; Cell Res., 35:913-916, 2025; PubMed: 40813798; DOI: 10.1038/s41422-025-01165-w

Experimental method

ELECTRON MICROSCOPY (3.86 Å)