9IE5

Human Deoxyhypusine Synthase Fragment Screening Campaign - ligand VT00230

This is a non-PDB format compatible entry.

Summary for 9IE5

• Entry DOI: 10.2210/pdb9ie5/pdb
• Descriptor: Deoxyhypusine synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-(4-fluorophenyl)-1~{H}-pyrazol-3-amine, ... (5 entities in total)
• Functional Keywords: fragment screening, polyamines, high-throughput, posttranslational modifications, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 83888.38

Authors

Wilk, P.,Wator-Wilk, E.,Krojer, T.,Grudnik, P. (deposition date: 2025-02-15, release date: 2026-01-21)

• Primary citation: Wilk, P.,Wator-Wilk, E.,Muszak, D.,Kochanowski, P.,Krojer, T.,Grudnik, P.; Crystallographic fragment screening supports tool compound discovery and reveals conformational flexibility in human deoxyhypusine synthase; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.43 Å)