9IDZ

Human Deoxyhypusine Synthase Fragment Screening Campaign - ligand VT00221

Summary for 9IDZ

• Entry DOI: 10.2210/pdb9idz/pdb
• Descriptor: Deoxyhypusine synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (4R)-2-METHYLPENTANE-2,4-DIOL, ... (5 entities in total)
• Functional Keywords: fragment screening, polyamines, high-throughput, posttranslational modifications, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 83678.20

Authors

Wilk, P.,Wator-Wilk, E.,Krojer, T.,Grudnik, P. (deposition date: 2025-02-15, release date: 2026-01-21)

• Primary citation: Wilk, P.,Wator-Wilk, E.,Muszak, D.,Kochanowski, P.,Krojer, T.,Grudnik, P.; Crystallographic fragment screening supports tool compound discovery and reveals conformational flexibility in human deoxyhypusine synthase; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.44 Å)