9IDI
Human Deoxyhypusine Synthase Fragment Screening Campaign - ligand VT00154
This is a non-PDB format compatible entry.
Summary for 9IDI
| Entry DOI | 10.2210/pdb9idi/pdb |
| Descriptor | Deoxyhypusine synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, imidazo[1,2-a]pyridin-2-ylmethanamine, ... (6 entities in total) |
| Functional Keywords | fragment screening, polyamines, high-throughput, posttranslational modifications, transcription |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 83860.44 |
| Authors | Wilk, P.,Wator-Wilk, E.,Krojer, T.,Grudnik, P. (deposition date: 2025-02-15, release date: 2026-01-21) |
| Primary citation | Wilk, P.,Wator-Wilk, E.,Muszak, D.,Kochanowski, P.,Krojer, T.,Grudnik, P. Crystallographic fragment screening supports tool compound discovery and reveals conformational flexibility in human deoxyhypusine synthase To Be Published, |
| Experimental method | X-RAY DIFFRACTION (1.47 Å) |
Structure validation
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