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9IDI

Human Deoxyhypusine Synthase Fragment Screening Campaign - ligand VT00154

This is a non-PDB format compatible entry.
Summary for 9IDI
Entry DOI10.2210/pdb9idi/pdb
DescriptorDeoxyhypusine synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, imidazo[1,2-a]pyridin-2-ylmethanamine, ... (6 entities in total)
Functional Keywordsfragment screening, polyamines, high-throughput, posttranslational modifications, transcription
Biological sourceHomo sapiens (human)
More
Total number of polymer chains2
Total formula weight83860.44
Authors
Wilk, P.,Wator-Wilk, E.,Krojer, T.,Grudnik, P. (deposition date: 2025-02-15, release date: 2026-01-21)
Primary citationWilk, P.,Wator-Wilk, E.,Muszak, D.,Kochanowski, P.,Krojer, T.,Grudnik, P.
Crystallographic fragment screening supports tool compound discovery and reveals conformational flexibility in human deoxyhypusine synthase
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.47 Å)
Structure validation

247947

PDB entries from 2026-01-21

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