9IAX

DNA-PK, LX4, XLF - Catalytic domain of L4

Summary for 9IAX

• Entry DOI: 10.2210/pdb9iax/pdb
• EMDB information: 52786
• Descriptor: DNA-dependent protein kinase catalytic subunit, X-ray repair cross-complementing protein 6, X-ray repair cross-complementing protein 5, ... (8 entities in total)
• Functional Keywords: kinase, nhej, cryo-em, dna-pk, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 899782.66

Authors

Chaplin, A.K.,Hall, C. (deposition date: 2025-02-11, release date: 2026-03-04, Last modification date: 2026-10-14)

• Primary citation: Goff, N.,Hall, C.,Mikova, M.,Parkhi, G.,Sundar, S.,Walia, A.,Hardwick, S.,Modesti, M.,Schmidt, J.,Yu, K.,Chaplin, A.,Meek, K.; Shared interfaces: a recurrent mechanism that may serve to promote or impede NHEJ progression via DNA ligase IV-dependent end-synapsis; Nucleic Acids Res., 2026

Experimental method

ELECTRON MICROSCOPY (3.97 Å)