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9IAM

Structure of cyclodipeptide synthase from Nocardia brasiliensis (Nbra-CDPS) in complex with alanylated RNA microhelices analogues mimicking Ala-tRNA-Ala substrate

This is a non-PDB format compatible entry.
Summary for 9IAM
Entry DOI10.2210/pdb9iam/pdb
Related9I5M
DescriptorCyclodipeptide synthase, RNA (5'-R(P*GP*GP*GP*GP*CP*UP*AP*UP*UP*CP*GP*UP*AP*GP*CP*UP*CP*CP*AP*CP*C)-3') (2 entities in total)
Functional Keywordsnonribosomal peptide synthetases, cyclodipeptide synthases, ligase, trna, rna binding protein
Biological sourceNocardia brasiliensis ATCC 700358
More
Total number of polymer chains19
Total formula weight432986.38
Authors
Marouf, Z.,Charbonnier, J.B.,Fernandez Varela, P.,Legrand, P. (deposition date: 2025-02-11, release date: 2026-03-11)
Primary citationMarouf, Z.,Charbonnier, J.B.,Fernandez Varela, P.,Lescop, E.,Morellet, N.,Gondry, M.
The tRNA moieties of two consecutive substrates of a cyclodipeptide synthase share a common binding site as demonstrated with RNA microhelices that mimic their acceptor arms.
To Be Published,
Experimental method
X-RAY DIFFRACTION (3.61 Å)
Structure validation

250359

건을2026-03-11부터공개중

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