9I7V

EAAT1 thermostabilized mutant in Complex with Rubidium, and the allosteric inhibitor UCPH101 in DDS/CHS

Summary for 9I7V

• Entry DOI: 10.2210/pdb9i7v/pdb
• Related: 9I7M
• EMDB information: 52663
• Descriptor: EAAT1 thermostabilized mutant, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ... (4 entities in total)
• Functional Keywords: transport protein, glutamate transport, salipro, l-aspartate, membrane protein
• Biological source: Homo sapiens
• Total number of polymer chains: 3
• Total formula weight: 173004.61

Authors

Horn, G.,Fu, L.,Madej, M.G.,Ziegler, C. (deposition date: 2025-02-02, release date: 2026-02-18)

• Primary citation: Horn, G.,Fu, L.,Madej, M.G.,Ziegler, C.; CryoEM Structure of EAAT1 thermostabilized mutant in Complex with L-Asp, Metal Ions, and the allosteric inhibitor UCPH101 in Salipro and DDS/CHS; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.84 Å)