9I3U

Cryo-EM structure of the AGR2 dimer in complex with the monomeric IRE1beta luminal domain

Summary for 9I3U

• Entry DOI: 10.2210/pdb9i3u/pdb
• EMDB information: 52616
• Descriptor: Anterior gradient protein 2 homolog, Serine/threonine-protein kinase/endoribonuclease IRE2 (2 entities in total)
• Functional Keywords: endoplasmic reticulum (er) / molecular chaperones/ protein multimerisation/ unfolded protein response (upr), chaperone
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 79084.25

Authors

Yan, Y.,Hardwick, S.,Tung, J.,Ron, D. (deposition date: 2025-01-24, release date: 2025-10-22)

• Primary citation: Neidhardt, L.,Tung, J.,Ron, D.,Yan, Y.; A structural basis for chaperone repression of stress signalling from the endoplasmic reticulum; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.9 Å)