9I10

Human protein kinase CK2 alpha in complex with TN12

This is a non-PDB format compatible entry.

Summary for 9I10

• Entry DOI: 10.2210/pdb9i10/pdb
• Related: 8C6M 8C6N 9I0Z
• Descriptor: Casein kinase II subunit alpha, (2~{Z},5~{Z})-5-[(4-methoxy-3-oxidanyl-phenyl)methylidene]-2-(3-methylphenyl)imino-1,3-thiazolidin-4-one, SULFATE ION, ... (5 entities in total)
• Functional Keywords: kinase domain, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 39994.47

Authors

Dalle Vedove, A.,Cazzanelli, G.,Lolli, G. (deposition date: 2025-01-15, release date: 2025-02-26)

• Primary citation: Cazzanelli, G.,Dalle Vedove, A.,Broso, F.,Burigotto, M.,Zasso, J.,Aiello, G.,Zonta, F.,Astolfi, A.,Barreca, M.L.,Ruzzene, M.,Tiberi, L.,Fava, L.L.,Quattrone, A.,Lolli, G.; Switching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)