9HXG

Bacterial antiviral defense protein Ec2ApeA from Escherichia coli strain 2-156-04_S4_C1 saturated with pdCpdG dinucleotide (HEPN active site mutant R502A)

Summary for 9HXG

• Entry DOI: 10.2210/pdb9hxg/pdb
• EMDB information: 52475
• Descriptor: Bacterial antiviral defense protein Ec2ApeA from Escherichia coli strain 2-156-04_S4_C1 (HEPN active site mutant R502A), DNA (5'-D(P*CP*G)-3'), ZINC ION (3 entities in total)
• Functional Keywords: apea, hepn domain, bacterial antiviral defence, rna binding protein
• Biological source: Escherichia coli 2-156-04_S4_C1; More
• Total number of polymer chains: 20
• Total formula weight: 698267.69

Authors

Sasnauskas, G.,Juozapaitis, J.,Puteikiene, R.,Tamulaitiene, G. (deposition date: 2025-01-07, release date: 2026-07-22)

• Primary citation: Juozapaitis, J.,Silanskas, A.,Ruksenaite, A.,Puteikiene, R.,Truncaite, L.,Songailiene, I.,Tamulaitiene, G.,Siksnys, V.,Sasnauskas, G.; ApeA is a deoxyribodinucleotide binding antiviral defense system targeting tRNA; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.43 Å)