9HXF

Bacterial antiviral defense protein Ec2ApeA from Escherichia coli strain 2-156-04_S4_C1 saturated with pdGpdG dinucleotide (HEPN active site mutant R502A)

Summary for 9HXF

• Entry DOI: 10.2210/pdb9hxf/pdb
• EMDB information: 52474
• Descriptor: Bacterial antiviral defense protein Ec2ApeA from Escherichia coli strain 2-156-04_S4_C1 (HEPN active site mutant R502A), DNA (5'-D(P*GP*G)-3'), ZINC ION (3 entities in total)
• Functional Keywords: apea, hepn domain, bacterial antiviral defence, rna binding protein
• Biological source: Escherichia coli 2-156-04_S4_C1; More
• Total number of polymer chains: 20
• Total formula weight: 698667.93

Authors

Sasnauskas, G.,Juozapaitis, J.,Puteikiene, R.,Tamulaitiene, G. (deposition date: 2025-01-07, release date: 2026-07-22)

• Primary citation: Juozapaitis, J.,Silanskas, A.,Ruksenaite, A.,Puteikiene, R.,Songailiene, I.,Truncaite, L.,Tamulaitiene, G.,Siksnys, V.,Sasnauskas, G.; ApeA is a deoxyribodinucleotide binding antiviral defense system targeting tRNA; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.12 Å)