9HWE

SMAD4 MH2, residues 314-552

Summary for 9HWE

• Entry DOI: 10.2210/pdb9hwe/pdb
• Descriptor: Mothers against decapentaplegic homolog 4, 1,2-ETHANEDIOL, SULFATE ION, ... (4 entities in total)
• Functional Keywords: transcription factor, smad4 mh2 domain, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 26496.07

Authors

Torner, C.,Condeminas, M.,Pluta, R.,Pous, J.,Macias, M.J. (deposition date: 2025-01-03, release date: 2026-07-15)

• Primary citation: Torner, C.,Condeminas, M.,Pluta, R.,Aragon, E.,Khan, R.J.,Martin-Malpartida, P.,Rodriguez de Regil, M.,Pous, J.,Humm, A.-S.,Niebling, S.,Garcia-Alai, M.,Marquez, J.A.,Martinez, A.,Macias, M.J.; (RUNNING TITLE:) Insights into the structure-activity relationship of SMAD4 variants linked to Myhre syndrome and hereditary hemorrhagic telangiectasia; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)