9HPY

Crystal structure of avibactam bound to OXA-57

Summary for 9HPY

• Entry DOI: 10.2210/pdb9hpy/pdb
• Descriptor: Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide (3 entities in total)
• Functional Keywords: class-d beta-lactamase complex with a inhibitor, antimicrobial protein
• Biological source: Burkholderia pseudomallei
• Total number of polymer chains: 1
• Total formula weight: 27300.79

Authors

Bragginton, E.C.,Hinchliffe, P.,Spencer, J. (deposition date: 2024-12-16, release date: 2025-12-24)

• Primary citation: Bragginton, E.C.,Colenso, C.K.,Calvopina, K.,Hinchliffe, P.,Shaw, J.M.,Tooke, C.L.,Seng, R.,Chantratita, N.,Schofiled, C.J.,Spencer, J.; Structure and dynamics of Burkholderia pseudomallei OXA-57, a distinctive low efficiency class D beta-lactamase with carbapenem-hydrolyzing activity; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.48 Å)