9HJN

Structure of UDP-Galactose-4-epimerase (GalE) bound to fragment from Diamond XChem experiment.

Summary for 9HJN

• Entry DOI: 10.2210/pdb9hjn/pdb
• Related: 9HI0 9HI1 9HI2
• Descriptor: UDP-glucose 4-epimerase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, N-ethyl-N'-(5-methyl-1,2-oxazol-3-yl)urea, ... (8 entities in total)
• Functional Keywords: fragment, epimerase, carbohydrate processing, carbohydrate
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 79204.63

Authors

Browne, W. (deposition date: 2024-11-29, release date: 2025-12-10)

• Primary citation: Browne, W.,Purkiss, A.G.,Weckwerth, T.,Ogrodowicz, R.,Prema, R.,Kunzelmann, S.,Roustan, C.,Mouilleron, S.,Schumann, B.; Identification of Novel Inhibitors of Human UDP-Galactose-4-Epimerase (GalE) by Fragment-Based Lead Discovery; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.651 Å)