9HCA

The L2A-II alpha-synuclein fibril in the presence of MODAG-005 (long incubation)

Summary for 9HCA

• Entry DOI: 10.2210/pdb9hca/pdb
• Related: 9hc6
• EMDB information: 52042
• Descriptor: Alpha-synuclein (1 entity in total)
• Functional Keywords: alpha-synuclein, fibril, modag-005, pet tracer, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 15
• Total formula weight: 217141.62

Authors

Frieg, B.,Kim, M.,Griesinger, C.,Schroeder, G.F. (deposition date: 2024-11-08, release date: 2025-11-19)

• Primary citation: Kim, M.,Matthes, D.,Frieg, B.,Leonov, A.,Ryazanov, S.,Bleher, D.,Grotegerd, A.-K.,Dienemann, C.,Giese, A.,Schroeder, G.F.,Becker, S.,Herfert, K.,de Groot, B.L.,Andreas, L.B.,Griesinger, C.; Structural insights into binding of novel PET tracer MODAG-005 to lipidic alpha-synuclein fibrils; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.7 Å)