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9HC8

The L2C alpha-synuclein fibril in the presence of MODAG-005 (short incubation)

Summary for 9HC8
Entry DOI10.2210/pdb9hc8/pdb
Related9hc6
EMDB information52040
DescriptorAlpha-synuclein (1 entity in total)
Functional Keywordsalpha-synuclein, fibril, modag-005, pet tracer, protein fibril
Biological sourceHomo sapiens (human)
Total number of polymer chains10
Total formula weight144761.08
Authors
Frieg, B.,Kim, M.,Griesinger, C.,Schroeder, G.F. (deposition date: 2024-11-08, release date: 2025-11-19)
Primary citationKim, M.,Matthes, D.,Frieg, B.,Leonov, A.,Ryazanov, S.,Bleher, D.,Grotegerd, A.-K.,Dienemann, C.,Giese, A.,Schroeder, G.F.,Becker, S.,Herfert, K.,de Groot, B.L.,Andreas, L.B.,Griesinger, C.
Structural insights into binding of novel PET tracer MODAG-005 to lipidic alpha-synuclein fibrils
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.82 Å)
Structure validation

247035

PDB entries from 2026-01-07

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