9HAO

BDM91531 inhibitor bound to the transmembrane domain of AcrB

Summary for 9HAO

• Entry DOI: 10.2210/pdb9hao/pdb
• Related: 8QZQ 8QZT
• Descriptor: Multidrug efflux pump subunit AcrB, [3-(3-chloranyl-2-piperazin-1-yl-quinolin-6-yl)phenyl]methanamine, DECANE, ... (16 entities in total)
• Functional Keywords: rnd multidrug efflux pump, antimicrobial resistance, allosteric inhibitor, intermediate conformational state, transport protein
• Biological source: Escherichia coli K-12; More
• Total number of polymer chains: 5
• Total formula weight: 394706.89

Authors

Mueller, R.T.,Herrmann, A.,Pos, K.M. (deposition date: 2024-11-04, release date: 2025-11-12)

• Primary citation: Boernsen, C.,Mueller, R.T.,Pos, K.M.; Molecular mechanism of transition-state inhibitors of bacterial antibiotic efflux pumps; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.94 Å)